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Concerta 36mg methylphenidate original online

$6.00$190.00

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Price per bottle$290.00 $190.00instock
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Price per tablet$13.00 $6.00instock
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Description

Concerta 36mg methylphenidate

Concerta 36mg methylphenidate indicates for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients 6 years of age and older and for the treatment of narcolepsy.

Methylphenidate contains a black box warning stating that CNS stimulants. Also, Including methylphenidate-containing products and amphetamines. Also, Have a high potential for abuse and dependence. Therefore, This abuse potential is likely related to the effects associated with higher doses of methylphenidate. Also, which induce surface expression of the dopamine transporter (DAT). In particular, increased dopamine in key brain areas is associated with the reinforcing and addictive properties of psychostimulants such as methylphenidate, and even amplifies the potency and reinforcing effects of other drugs of abuse such as amphetamines, making ADHD sufferers more susceptible to their addictive effects. Concerns about abuse potential have spurred research into medications with fewer effects on DAT and the use of non-stimulant ADHD medications including Atomoxetine and Guanfacine.

Concerta 36mg methylphenidate

Concerta 36 mg methylphenidate

Concerta 36 mg methylphenidate

Pharmacodynamics | Concerta 36mg XR

Methylphenidate is a racemic mixture which comprises of the d- and l-isomers. Also, The d-isomer is more pharmacologically active than the l-isomer. Therefore, Radioligand binding studies demonstrate that binding of methylphenidate in the brain localizes to dopamine-rich areas. Also, In particular in the prefrontal cortex which demonstrates to play a prominent role in ADHD pathophysiology . Therefore,  In a number of animal models, methylphenidate enhances locomotor activity and induces stereotypic behaviors.

Toxicity

Symptoms of overdose include vomiting, agitation, tremors, hyperreflexia,

Also, muscle twitching, convulsions (may be followed by a comma).

Euphoria, confusion, hallucinations, delirium, sweating, flushing, headache,

hyperpyrexia, tachycardia, palpitations, cardiac arrhythmias, hypertension, mydriasis,

Finally, Dryness of mucous membranes. LD50=190mg/kg (orally in mice)

 

Name                          Methylphenidate

Accession Number     DB00422  (APRD00657)

Type                              Small Molecule

Groups                          Approved, Investigational

 

Additional information

QTY

Price per bottle, Price per tablet

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